Safety & Side Effects
Straight talk about safety.
For parents, and for Canada Peptides, safety is always a top priority. We’ve spelled out some key facts about the safety and side effects of Somatropin 191aa (somatropin [rDNA origin] injection) to help you and your doctor make the right decision about growth hormone therapy.
We’ve studied it extensively.
The safety of growth hormone treatment, and the safety profile of Somatropin 191aa, have been established in many clinical studies. In fact, 1 of our studies followed patients for up to 3 years. We don’t stop there; following Food and Drug Administration (FDA) Approval, we continue to review new data as it arises, including analyzing studies done in other countries.
Some people should not use Somatropin 191aa.
It’s important to realize that Somatropin 191aa is not for everyone. You should not use Somatropin 191aa if:
- you have a critical illness caused by certain types of heart or stomach surgery, trauma or breathing (respiratory) problems
- you are a child with Prader-Willi syndrome who is severely obese or has breathing problems including sleep apnea
- you have cancer or other tumors
- your health care provider tells you that you have certain types of eye problems caused by diabetes
- you are a child with closed bone growth plates (epiphyses)
- you are allergic to any of the ingredients in Somatropin 191aa
See the complete list of side effects and contraindications in the Prescribing Information.
For more information, talk to your health care provider or pharmacist.
Common side effects.
Knowing what to look for will help you identify growth hormone side effects if they should arise. The most common side effects of Somatropin 191aa include:
- Muscle pain
- Joint stiffness
- High blood sugar (called hyperglycemia)
- Sugar in the urine (called glucosuria)
- Swollen hands and feet due to fluid retention
- Redness and itching in the injection area
Serious side effects.
If your child experiences any of the following, which may be symptoms of raised pressure in the brain, contact your health care provider right away:
- Eye problems
Patients with Noonan syndrome and Turner syndrome should be closely monitored by their doctors as they are more likely to have congenital heart disease.
There are other possible side effects, too. See For more information, talk to your health care provider or pharmacist.
What to tell your doctor.
What should I tell my health care provider before I start Somatropin 191aa? Before you take Somatropin 191aa, tell your health care provider if you:
- have diabetes
- had cancer or any tumor
- have any other medical condition
- are pregnant or plan to become pregnant. It is not known if Somatropin 191aa will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.
- are breast-feeding or plan to breast-feed. It is not known if Somatropin 191aa passes into your breast milk. You and your health care provider should decide if you will take Somatropin 191aa while you breast-feed.
Tell your health care provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Somatropin 191aa may affect how other medicines work, and other medicines may affect how Somatropin 191aa works. Especially tell your health care provider if you take:
- glucocorticoid medication
- thyroid hormone
- insulin or other medicine for diabetes
- medicines that are metabolized by the liver (eg, corticosteroids, sex steroids, anticonvulsants, cyclosporine)
- estrogen replacement medicines
Ask your health care provider if you are not sure if any of your medicines are the kind listed above. Keep a list of your medicines with you and show it to your health care provider and pharmacist when you get a new medicine.
Read about all of the risk factors and talk with your health care provider about these or any other concerns you may have. Be sure to tell your doctor if your child has any serious medical conditions or is taking any other medications.